Folli-optimism

 My husband and I were really freaked out by all of the needles involved in Follistim, but it really hasn't been so bad- especially because we are finally, finally seeing some changes so it all feels worth it. Side effects have been minimal (follistim farts and gas pains, :) and are a piece of cake compared to Clomid and Femara. I wish we could have just started here to begin this journey.

Fun, follistim freebies: 

a. The nurse mentioned that there might be some extra meds in the 300iu pen and turns out this is quite common! It has given me two free days! Woo hoo! I love free when it comes to this pricey adventure! Well, I love free when it comes to anything! (Hotel shampoos and Starbucks Splendas anyone?)

b. The cool red container for the needles from the pharmacy below the fertility clinic. You can get fined if you discard the needles inappropriately so you bring this container back to the doc to empty it there. Multiple times this weekend, I have wanted to use it as a vase. Maybe I will when I can celebrate the end of this process!

c. Rubbing alcohol wipes. When the nurse taught us how to use the follipen, she asked if we had alcohol in the house to prep the injection site. Dead serious, my husband responded intently and matter-of-factly, "Oh yes, vodka. Got it." HA! I almost died on the spot! She was very gracious and corrected him. We had to get some from the pharmacy and when the woman at the pharmacy saw us looking for it on the shelf, she gave us a huge stack of single wipes for free!

 

Follistim Day 6 Monitoring (Saturday)

-Bloodwork showed my Estrogen increased to 74 from the 20s!

-3 follicles growing larger (2 on the right, 1 on the left) and lots of little ones, largest at about 12 mmm
-My husband and I were so excited that two follicles were growing on the right so even though you are supposed to switch injection sides each night, we excitedly decided to inject only on the right to be closest to our potential little gifts. Silly, I know, but everyone needs something to keep their hopes up!
-Severe gas pains have subsided, not sure if it's from the interaction between the metformin and the follistim or what. Thank goodness ! 
-Continue with 50iu injects nightly

Follistim Day 8 Monitoring (Monday)

- Bloodwork showed increase in Estrogen to 102!

-6 larger follicles now, largest at 14.5mm! (Getting closer to the 18mm needed to trigger!) Hilarious that the largest ones were now on the left and 1 large on on the right. I guess it doesn't matter where you inject! Felt amazing to see such a large follicle today. I could really tell the difference and my ultrasound technician was so excited for me. We were both celebrating! Hoping that I got the first glimpse of our future little one this morning!

-Filled with so much hope! Just hoping and praying that only 1-3 will get big enough.

-Going back in two days to see if anything changes!
-Continue with 50iu injects nightly

Follistim Day 10 Monitoring (Wednesday) 

 Went in again for monitoring- good news!

-three follicles measured 19.0, 16.6, 10.7

-estrogen level is 248. 

-trigger this evening with the Ovidrel injection and get busy

-start prometrium on Saturday

-schedule for pregnancy test two weeks later

Our Fertility Journey

It's been a long one so far with a lot of highs and lows. We are still hoping and wishing for our own little one.

A little about myself: I am now 29 years old, happy and healthy but after about 100 days of amenorrhea (lack of period) following birth control last year, I was diagnosed with PCOS via ultrasound and was put on progesterone to start my period. I switched from my general women's health doctor to a specialized ob/gyn who also confirmed the PCOS through another transvaginal ultrasound. My husband's sperm was tested and he has no diagnosed issues. She started me on progesterone again after a long cycle and I tried one round of Clomid 50mg on which I did not ovulate. I began another round of progesterone and got my period after 50 days. I completed a second round of Clomid at 100mg but again, failed to respond and ovulate. Following the second round's failure, my doctor broke up with me and referred me to a fertility clinic.
 


Feb/March 2013- Preconception Meeting with women's health doctor, given the green light. Began taking prenatal vitamins

May 21, 2013- Take out last NuvaRing

May 24, 2013- NuvaRing induced period

July 29, 2013- Start officially tracking CM on fertility friend

August 17, 2013- CD 86, Start officially temping

August 26, 2013- CD 95 Start Metformin 1000mg, t/v Ultrasound. Blood work (PCOS diagnosis)

August 29, 2013- Metformin 1500mg

August 30, 2013- Bloodwork done

Sept 4, 2013 Horribly sick, stomach pains

Sept 5, 2013 Back down to 1000mg Met for a week, then back to 1500mg

Sept 26, 2013 Switched Drs to specialist, t/v ultrasound confirms pcos, prescribed Provera for 10 days to induce a period.

Oct 5, 2013 Last Provera pill CD 136

Oct 7, 2013 Provera Period #1! (Light, no major cramps or symptoms)

Oct 9- blood test, fsh, progesterone, wbc- not ovulating

Nov 2- Hubby SA- all clear! (rushed to get done because we thought I'd start provera/clomid but dr said to wait two more weeks to see if my period would come first...)

Nov 19- No luck, Provera round 2 (cd 44)

Dec 2- Provera Period #2! (after 56 days, more substantial and longer flow than p#1)

Dec 6- Begin Clomid Round 1 (cd 5-9)
Dec/Jan Test with OPKs and temping, did not detect ovulation. Blood work confirmed this.

Jan 21- Provera Period #3 began after 10 days of Provera round 3. (50 Days...)

Jan 25-29 Clomid increased to 100mg Round 2 (Taken days 5-9)

Feb 4- Begin Acupunture! :)

Feb- More bloodwork confirms that I did not respond to Clomid

March 7- Ob/Gyn breaks up with me, telling me I'm infertile and she can't help me any more, refers me to fertility center and asks if I have considered adoption... obviously devastated

March 17- Was scheduled for a 4/21 appt, but got a new patient appointment at fertility center because of a snow day cancellation and a lot of Irish luck! Dr. Hope says he feels confident he can help us get pregnant! Start Provera round 4!

March 26- Genetic testing is in- I'm a carrier for SMA.:(  DH needs to be tested to see if he's a carrier too. If so, it will reset our plan again. 2ww for results.

March/April ??-Provera Period #4
April 26- Start Clomid (days 3-7), plan to take trigger shot and progesterone if all goes well
May 4th- Day 11 ultrasound and blood work, one follicle at 7.4mm (too small), others tiny, no trigger shot necessary
May 8th- Another u/s and more blood work... failed again
May 13- Day 20, Another u/s and more blood work... failed again, no Clomid response, begin Femara 2.5mg
May 26- Femara failed, began Follistim at 50iu and continue Metformin/Acupunture (estrogen dropped to 25, yikes!)
June 6- Estrogen jumped  to 102 -6 larger follicles, largest at 14.5mm
June/July- Failed injection cycles
August- Successful with follistim and ovidril but ended in chemical pregnancy
September- Again successful, but same result 
October 2014- Started with follistim and converted to IVF
Oct 8- Egg Retrieval- 28 eggs, 22 mature, 18 fertilized!